Protoplasma specializes in the area between structural and molecular analysis of biological systems from gene expression to the sub- and supracellular levels. The journal offers articles on structural and functional cell biology of plants and animals, protists, fungi as well as prokaryotes.Coverage includes biogenesis, dynamics, and energetics of membrane compartments; targeting and trafficking of macromolecules; cellular dynamics, intracellular transport, and whole-cell locomotion; structure, dynamics, and molecular components of the cytoskeleton; signaling and regulatory cascades; the cell cycle and cell-to-cell communication; medical aspects of cell biology.Besides research, rapid communications, and comprehensive review articles, Protoplasma publishes reviews of discoveries, and opportunities at the cutting edge of research under the headings New Ideas in Cell Biology.

原生質(zhì)專門研究生物系統(tǒng)的結(jié)構(gòu)和分子分析，從基因表達到亞細(xì)胞和超細(xì)胞水平。該雜志提供有關(guān)植物和動物、原生生物、真菌以及原核生物的結(jié)構(gòu)和功能細(xì)胞生物學(xué)的文章。覆蓋范圍包括膜室的生物發(fā)生、動力學(xué)和能量學(xué);大分子的靶向和轉(zhuǎn)運;細(xì)胞動力學(xué)、細(xì)胞內(nèi)運輸和全細(xì)胞運動;細(xì)胞骨架的結(jié)構(gòu)、動力學(xué)和分子組成;信號和調(diào)節(jié)級聯(lián);細(xì)胞周期和細(xì)胞間通訊;細(xì)胞生物學(xué)的醫(yī)學(xué)方面。除了研究、快速通訊和全面的綜述文章外，原生質(zhì)還在細(xì)胞生物學(xué)新觀點的標(biāo)題下發(fā)表對發(fā)現(xiàn)和前沿研究機會的綜述。