Nitric Oxide includes original research, methodology papers and reviews relating to nitric oxide and other gasotransmitters such as hydrogen sulfide and carbon monoxide. Special emphasis is placed on the biological chemistry, physiology, pharmacology, enzymology and pathological significance of these molecules in human health and disease. The journal also accepts manuscripts relating to plant and microbial studies involving these molecules.

一氧化氮包括關于一氧化氮和其他氣體傳遞物如硫化氫和一氧化碳的原始研究、方法論文和綜述。重點介紹了這些分子的生物化學、生理學、藥理學、酶學和病理意義。該雜志還接受涉及這些分子的植物和微生物研究的手稿。